心臓領域の悪液質とサルコペニアの研究のミニレビュー論文を紹介します。
Coats AJ. Research on cachexia, sarcopenia and skeletal muscle in cardiology. J Cachexia Sarcopenia Muscle. 2012 Nov 16. [Epub ahead of print]
抄録しか読めていませんが、過去3年間の肥満パラドックス、原因、治療に関するミニレビュー論文のようです。がん、COPD、慢性腎不全、慢性肝不全の悪液質でも研究が進んでいるようです。心筋のサルコペニアに関する研究も増えてほしいですね。
Abstract
BACKGROUND:
The awareness of cardiac
cachexia, i.e. involuntary weight loss in patients with underlying cardiovascular disease, has increased over the last two decades.
METHODS AND RESULTS:
This mini-review looks at recent
research in the cardiovascular literature that is relevant to the areas of interest of the Journal of
Cachexia,
Sarcopenia and
Muscle. It identifies significant
research in the last 3 years on the obesity paradox, the causes and effects of
skeletal muscle wasting, animal models of
cachexia and emerging treatment ideas in cardiac
cachexia.
CONCLUSIONS:
Assuming a similar literature in the fields of cancer, chronic obstructive pulmonary disease, chronic renal failure and chronic liver failure, the emergence of
cachexia as a vibrant area of clinical and experimental
research seems assured.
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